Quarterly report pursuant to Section 13 or 15(d)

Statement of Convertible Preferred Stock and Stockholders' Equity (Deficit)

Statement of Convertible Preferred Stock and Stockholders' Equity (Deficit) (USD $)	Total	Preferred Stock [Member]	Initial Public Offering [Member]	IPO Over-Allotment [Member]	Convertible Notes [Member]	Common Stock [Member]	Common Stock [Member] Preferred Stock [Member]	Common Stock [Member] Initial Public Offering [Member]	Common Stock [Member] IPO Over-Allotment [Member]	Common Stock [Member] Convertible Notes [Member]	Additional Paid-In Capital [Member]	Additional Paid-In Capital [Member] Preferred Stock [Member]	Additional Paid-In Capital [Member] Initial Public Offering [Member]	Additional Paid-In Capital [Member] IPO Over-Allotment [Member]	Additional Paid-In Capital [Member] Convertible Notes [Member]	Accumulated Deficit [Member]	Accumulated Deficit [Member] Preferred Stock [Member]	Series A Convertible Preferred Stock [Member]	Series A Convertible Preferred Stock [Member] Preferred Stock [Member]	Series B Convertible Preferred Stock [Member]	Series B Convertible Preferred Stock [Member] Preferred Stock [Member]	Series C Convertible Preferred Stock [Member]	Series C Convertible Preferred Stock [Member] Preferred Stock [Member]	Series C-1 Convertible Preferred Stock [Member]	Series C-1 Convertible Preferred Stock [Member] Preferred Stock [Member]
Beginning Balance at Dec. 31, 2013	$ (52,910,500)					$ 101					$ 4,930,310					$ (57,840,911)		$ 1,964,283		$ 10,175,750		$ 27,752,294
Beginning Balance, Shares at Dec. 31, 2013						1,011,997												2,200,000		4,651,163		9,090,909
Issuance of preferred stock for license																								500,000
Issuance of preferred stock for license, Shares																								151,515
Issuance of securities in IPO			36,000,000	5,281,998				600	88				35,999,400	5,281,910
Issuance of securities in IPO, Shares								6,000,000	880,333
Issuance of common stock		40,392,327			30,632,689		686			520		44,860,093			30,632,169		(4,468,452)		(1,964,283)		(10,175,750)		(27,752,294)		(500,000)
Issuance of common stock, Shares							6,861,968			5,197,476									(2,200,000)		(4,651,163)		(9,090,909)		(151,515)
Financing cost of sale of securities in IPO	(6,644,713)										(6,644,713)
Cancellation of placement agent warrants	941,541										941,541
Net shares of common stock issued in relation to vesting of retention grants	532,451					13					532,438
Net shares of common stock issued in relation to vesting of retention grants, Shares						133,109
Share-based compensation	695,546										695,546
Net loss for the nine months ended September 30, 2014	(25,412,413)															(25,412,413)
Ending balance at Sep. 30, 2014	$ 29,508,926					$ 2,008					$ 117,228,694					$ (87,721,776)
Ending balance, Shares at Sep. 30, 2014						20,084,883