Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies - Additional Information (Detail)

v3.22.1
Commitments and Contingencies - Additional Information (Detail)
1 Months Ended 3 Months Ended
Dec. 31, 2020
Jan. 31, 2012
ft²
ExtensionOptions
Dec. 31, 2011
ExtensionOptions
Mar. 31, 2022
USD ($)
Mar. 31, 2021
USD ($)
Mar. 31, 2020
USD ($)
Mar. 31, 2019
USD ($)
Jan. 01, 2019
Loss Contingencies [Line Items]                
Non-cancellable operating lease, expiration date 2025-12 2027-12            
Extended lease agreement, date     2027-12          
Number of lease extension options | ExtensionOptions   2 2          
Lease renewal termination period   5 years 5 years          
Area of space relinquished from lease agreement | ft²   10,912            
Milestone payment       $ 810,000        
Operating lease, discount rate, percent               9.93%
Rockefeller University [Member]                
Loss Contingencies [Line Items]                
Annual maintenance fees payable in 2018         $ 200,000 $ 200,000 $ 200,000  
Annual maintenance fees payable after 2018         $ 200,000 $ 200,000 $ 200,000  
Percentage of royalty on net sales         5.00% 5.00% 5.00%  
Regulatory milestone payment         $ 5,000,000.0 $ 5,000,000.0 $ 5,000,000.0  
Royalty or sublicense payment       $ 0 $ 0      
License agreement termination notice period       60 days        
Period of termination after first commercial sale of first licensed product       10 years        
License agreement termination description       Each license agreement terminates upon the later of (i) the expiration or abandonment of the last licensed patent under the license agreement to expire or become abandoned, or (ii) 10 years after the first commercial sale of the first licensed product. The Rockefeller University may terminate any license agreement in the event of a breach of such agreement by the Company or if the Company challenges the validity or enforceability of the underlying patent rights. The Company may terminate any license agreement at any time on 60 days’ notice.