Quarterly report pursuant to Section 13 or 15(d)

Accrued Liabilities - Summary of Accrued Liabilities (Detail)

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Accrued Liabilities - Summary of Accrued Liabilities (Detail) - USD ($)
Mar. 31, 2019
Dec. 31, 2018
Payables and Accruals [Abstract]    
Accrued professional fees $ 788,471 $ 433,498
Accrued research and development service fees 702,884 2,076,764
Accrued compensation costs 452,324 1,585,689
Accrued facilities operation expenses 196,204 232,673
Other accrued liabilities 18,857 41,108
Total accrued liabilities $ 2,158,740 $ 4,369,732